老妇人被家人簇拥着

衰老,生命终结和癌症

This research theme includes a wide range of researchers from the biomedical, health and social sciences working on ageing, 临终关怀和癌症. We work in multi-disciplinary teams within, across and beyond the Faculty to help find solutions to the major global challenges of disease prevention and care for an ageing population.

标签内容:研究领域

Particular research areas within the ageing theme include:

  • Mechanisms of normal ageing using Drosophila as a model system
  • Age-related diseases, including neurodegenerative, joint and eye diseases
  • 姑息治疗和临终关怀
  • Place, health and wellbeing of ageing populations
  • 促进健康颐养的科技
  • Environmental/spatial epidemiology of cancer
  • 基因组稳定性
  • 致癌的分子机制
  • Supportive and end of life care 对于癌症患者

标签内容:研究成功

值得注意的研究成果包括:

  • Development of retro-inverted peptides as inhibitors of β-amyloid aggregation for the potential treatment of Alzheimer's disease
  • Development of α-synuclein as a biomarker for Parkinson's disease
  • Adoption of an ethical framework for good practice in telecare implementation by Age UK
  • Major revisions made to WHO policy document "Ensuring balance in national policies on controlled substances. Guidance for availability and accessibility of controlled medicines",由ATOME项目产生. Document published free in 15 languages and distributed worldwide
  • Co-ordination of research and development at governmental level in 12 resource-poor countries in central and eastern Europe to remove barriers to adequate pain control
  • Cochrane Review on case management approaches to home support for people with dementia (Protocol)
  • Demonstration of an epidemiological link between paternal occupational social class and various childhood cancers
  • The publication of several papers that collectively shed new light on the mechanisms involved in maintaining genome stability
  • 我们的 work on the biological effects of long wavelength ultraviolet (UV) radiation has informed the re-评价 of the health risks of UV radiation and how these should be communicated by the International Agency for 研究 on 癌症 and the International Commission for Non-Ionising Radiation Protection respectively
  • 研究ers in the IOELC have authored resource-stratified guidelines for policy-makers on the supportive, palliative and end-of-life care of cancer patients in Asia
  • 安妮Grinyer的书 缓和 & 儿童临终关怀 & 年轻人:家庭,临终关怀,医院, published by Blackwell in 2012, won an American Journal of Nursing Book of the Year Award.
  • Nancy Preston is developing an abdominal binder for malignant ascites (PI) from a 金沙体育 Impact Award

标签内容:癌症

This theme is addressed by all divisions within the Faculty, covering the full spectrum of cancer research from the molecular events that underpin its development to the management of care of those with life-limiting illnesses.

This interdisciplinary approach enables more comprehensive insights, so we can offer more effective interventions to improve the ageing process.

我们的 生物医学工作 improves understanding of the cellular and molecular biology of cancer.

这包括:

  • 癌症模型
  • cellular effects of exposure to carcinogens
  • 基因组稳定性和DNA修复
  • 细胞周期控制
  • molecular mechanisms of carcinogenesis

姑息治疗和临终关怀 对于癌症患者

  • understanding the needs of people with cancer
  • understanding the needs of those caring for them in both formal (e.g. 有报酬的职员)和非正式的(例如.g. 家庭成员)的能力

Care for people living with/surviving cancer

  • psychological mechanisms around survivorship
  • risk factors and behavioural decision-making

Environmental/spatial epidemiology of cancer

  • geographical impact on cancer incidence and survival

研究中心、小组和项目

  • 老龄化研究中心(C4AR)

    The Centre promotes and conducts high quality interdisciplinary research and research-led teaching around ageing, 老年人和与年龄有关的疾病.

  • International Observatory on End of Life Care

    The Observatory is internationally recognised for its high quality research, 评价, 教育, advocacy and consultancy designed to improve palliative and end of life care for patients and family carers.

  • 老龄化和神经科学

    Members of this research group contribute to the cross-faculty research theme on 老化 and to the 老龄化研究中心.

  • 癌症生物学与基因组稳定性

    Members of this research group contribute to the cross-faculty research theme on 老化.

  • Military Lives and Transformative Experiences

    The Military Lives and Transformative Experiences project was a study that aimed to consider the impact of personal narrative for older veterans.